schizophrenia – Page 2 – News and resources

Schizophrenia is a severe mental disorder affecting about 1% of the population worldwide, and is notoriously difficult to treat. Current treatments successfully target the disorder’s positive symptoms …

Apr 03 2026

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Alto halts work on PDE4 inhibitor after phase 2 schizophrenia failure

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Alto Neurosciences is halting work on its schizophrenia prospect after the brain-penetrant drug flunked a phase 2 study. The Bay Area biotech evaluated 10 days of treatment with t …

Apr 03 2026

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A gene mutation may trap the brain in the wrong reality in schizophrenia patients

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A newly identified gene mutation may help explain why schizophrenia patients struggle to update their understanding of reality. The mutation disrupts a brain circuit involved in flexible decision-making, causing mice...

Apr 02 2026

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Alto Neuroscience Misses Primary Endpoint in Schizophrenia Drug Study

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Alto Neuroscience missed the primary endpoint for a study of its ALTO-101 drug for the treatment of cognitive impairment associated with schizophrenia.

Apr 02 2026

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4 Ways to Find the Support You Need While Caring for a Person With Schizophrenia

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Caring for a friend or loved one with schizophrenia can often feel all-consuming. You may find yourself sacrificing work, school, or downtime during moments of crisis. Remaining hours, meanwhile, are...

Apr 01 2026

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Knowledge and Awareness of Reproductive Rights Among Women With Schizophrenia and Bipolar Affective Disorder – Cureus

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Knowledge and Awareness of Reproductive Rights Among Women With Schizophrenia and Bipolar Affective Disorder Cureus

Apr 01 2026

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A poorly “cleaned” brain can lead to schizophrenia

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How can we explain the onset of psychotic symptoms characteristic of schizophrenia? Despite their major and often irreversible impact on intellectual abilities and autonomy, the biological …

Mar 31 2026

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Would Earlier Initiation of Clozapine Improve First Episode Psychosis Outcomes?

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Higher response rates with clozapine after a single treatment failure raise questions about current recommendations and whether it should be used earlier in first-episode psychosis.